While Gareth Southgate has had to deal with the enforced absences of Kalvin Phillips and Jordan Pickford in Milan, the Three Lions boss has largely the core of the group available who have made deep runs into two consecutive major tournaments.
In place of Phillips, Jude Bellingham partners Declan Rice in midfield, with Jordan Henderson only just returning from a hamstring injury.
John Stones’ suspension sees Tottenham’s Eric Dier partner Harry Maguire in central defence, next to Reece James. Dier is finally back in the international fold after his stellar form at Spurs, while Maguire is set to continue to start despite his struggles at Manchester United.
Southgate had little time to tinker in personnel, although Pickford’s injury sees Nick Pope come in between the posts.
Harry Kane and Raheem Sterling, two pillars of Southgate’s success, once again start up front alongside Phil Foden and Bukayo Saka.
Despite his first call-up, Brentford striker Ivan Toney has not been included in England’s 23-man matchday squad. Marc Guehi and Ben Chilwell have also been left out.
Italy vs England lineups
England starting XI: Pope; Walker, James, Dier, Maguire, Saka; Rice, Bellingham, Sterling, Kane, Foden
Subs: Trippier, Ramsdale, Shaw, Grealish, Coady, Ward-Prowse, Tomori, Mount, Bowen, Alexander-Arnold, Henderson, Abraham
Italy starting XI: Donnarumma, Di Lorenzo, Bonucci (c), Acerbi, Toloi, Cristante, Jorginho, Dimarco, Raspadori, Barella, Scamacca
Subs: Meret, Vicario, Luiz Felipe, Pobega, Frattesi, Gnonto, Emerson, Zerbin, Grifo, Gabbiadini, Esposito, Bastoni